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Open Source Drug Discovery in Practice: A Case Study ...

Methods. A case study was chosen to research open source drug discovery projects in-depth in accordance with pre-defined research questions. Yin recommends a case study approach when the researcher wants to answer "how" and "why" questions, when an experiment is inappropriate or when it is necessary to understand the context in greater detail.

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Open Source Drug Discovery in Practice: A Case Study

2012-9-20 · Author Summary Open source drug discovery can be an influential model for discovering and developing new medicines and diagnostics for neglected diseases. It offers the opportunity to accelerate the discovery progress while keeping expenditures to a minimum by encouraging incremental contributions from volunteer scientists. Publishing raw data and …

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22 S. Ghosh et al. significant role as most patients are in the lowest income bracket of the society. This implies new drugs have to be developed in an innovative manner that allows delivery of drugs at low cost. Drug discovery is in general an

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2018-12-1 · TB is a worldwide infectious disease with more than 10.4 million cases and 1.7 million deaths reported in 2016 [] is commonly caused by 1) Mycobacterium tuberculosis (Mtb), frequently caused by 2) M. bovis and 3) M. africanum, and occasionally caused by 4) M. microti, 5) M. caprae, 6) M. canettii, 7) M. pinnipedii, 8) Dassie bacillus, 9) M. mungi, 10) M. orygis, …

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Thus, implementing a monitoring system by measuring surrogate biomarkers before and during treatment, could have a significant impact on the global burden of this disease, especially in …

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(PDF) Open Source Drug Discovery in Practice: A Case Study

aware of TBrowse (the publicly-available integrative genomics map) and of those seven had viewed TBrowse. As of February 16, 2012 there were 5,444 users registered in

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2011-11-1 · 1. Introduction. Tuberculosis is a major public health problem which infects one third of the world population and kills more than two million people every year. 1 The progression of Mycobacterium tuberculosis infection to disease manifestations characterized by chronic granuloma and caseation necrosis, or containment of the disease manifested by granuloma …

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See tbrowse for support values. * include/tbrowse + Defines for TBrowse and TBColumn Classes * include/button - Defines defined in TBrowse Walter Negro [xHarbour-developers] ChangeLog 2002-06-21 12:13 UTC-0800 Ron Pinkas

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